Indications A-Z

RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.

This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Indications starting with 'P'

Indication Treatments
Pain
Acetylsalicylic acid : Fever, pain – only adults (18 years old or older)
Acetylsalicylic acid : Pain – only adolescents (12 years - 18 years old)
Dexketoprofen : Mild to moderate pain – only adults (18 years old or older)
Dihydrocodeine : Severe pain in cancer and other chronic conditions – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Fentanyl : Breakthrough pain (BTP) – only adults (18 years old or older)
Levomepromazine : Severe pain – only adults (18 years old or older)
Levomepromazine : Severe pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Lornoxicam : Pain – only adults (18 years old or older)
Mefenamic acid : Pain – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Nitrous oxide (N2O) : Pain – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Paracetamol : Pain, fever – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pain at rest due to peripheral vascular disease
Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Pain of ear
Paracetamol : Pain, fever – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pain provoked by rest
Pentoxifylline : Peripheral vascular disease, intermittent claudication, rest pain – only adults (18 years old or older)
Painful swelling of joint
Ibuprofen : Painful swelling of joint – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pancreatic adenocarcinoma
Gemcitabine : Adenocarcinoma of the pancreas – only adults (18 years old or older)
Paclitaxel : Adenocarcinoma of pancreas – only adults (18 years old or older)
Pancreatic fistula
Lanreotide : Postoperative pancreatic fistula, postoperative small bowel fistula – only adults (18 years old or older)
Pancreatic insufficiency
Cimetidine : Pancreatic insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Cimetidine : Pancreatic insufficiency – only infants (40 days - 1 year old)
Cimetidine : Pancreatic insufficiency – only adults (18 years old or older)
Panic disorder
Alprazolam : Panic disorder with or without agoraphobia – only adults (18 years old or older)
Citalopram : Panic disorder with or without agoraphobia – only elderly (65 years old or older)
Citalopram : Panic disorder with or without agoraphobia – only adults (18 - 65 years old)
Escitalopram : Panic disorder with or without agoraphobia – only adults (18 years old or older)
Paroxetine : Panic disorder with and without agoraphobia – only adults (18 years old or older)
Sertraline : Panic disorder with or without agoraphobia – only adults (18 years old or older)
Venlafaxine : Panic disorder – only adults (18 years old or older)
Panuveitis in Behcet's syndrome
Ciclosporin : Behçet uveitis – only adults (18 years old or older)
Paralytic ileus
Neostigmine : Paralytic ileus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pyridostigmine : Paralytic ileus, post-operative urinary retention – only adults (18 years old or older)
Paraphilia
Cyproterone : Severe hypersexuality, sexual deviation – men, only adults (18 - 65 years old)
Paratyphoid fever
Amoxicillin : Typhoid and paratyphoid fever – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Parkinson's disease
Amantadine : Parkinson’s disease – only adults (18 years old or older)
Bromocriptine : Parkinson's Disease – only adults (18 years old or older)
Entacapone : Parkinson's disease – only adults (18 years old or older)
Levodopa : Parkinson's disease – only adults (18 years old or older)
Opicapone : Parkinson's disease – only adults (18 years old or older)
Piribedil : Parkinson's disease – only adults (18 years old or older)
Piribedil : Parkinson's disease – only adults (18 years old or older)
Pramipexole : Parkinson's disease – only adults (18 years old or older)
Rasagiline : Parkinson's disease – only adults (18 years old or older)
Ropinirole : Parkinson's disease – only adults (18 years old or older)
Ropinirole : Parkinson's disease – only adults (18 years old or older)
Rotigotine : Parkinson's disease – only adults (18 years old or older)
Rotigotine : Parkinson's disease – only adults (18 years old or older)
Safinamide : Parkinson's disease – only adults (18 years old or older)
Selegiline : Parkinson's disease – only adults (18 years old or older)
Selegiline : Parkinson's disease – only adults (18 years old or older)
Tolcapone : Idiopathic Parkinson's disease – only adults (18 - 65 years old)
Parkinsonism
Biperiden : Parkinsonism – only adults (18 years old or older)
Diphenhydramine : Parkinsonism – only adults (18 years old or older)
Orphenadrine : Parkinsonism – only adults (18 years old or older)
Paroxysmal atrial flutter
Propafenone : Ventricular arrhythmias, paroxysmal supraventricular tachyarrhythmias – only adults (18 years old or older)
Paroxysmal nocturnal dyspnea
Aminophylline : Pulmonary oedema, paroxysmal nocturnal dyspnoea, status asthmaticus, acute bronchospasm – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Paroxysmal nocturnal hemoglobinuria
Crovalimab : Paroxysmal nocturnal hemoglobinuria – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Danicopan : Paroxysmal nocturnal haemoglobinuria in patients who have residual haemolytic anaemia – only adults (18 years old or older)
Eculizumab : Paroxysmal nocturnal haemoglobinuria (PNH) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Eculizumab : Paroxysmal nocturnal haemoglobinuria (PNH) – only adults (18 years old or older)
Iptacopan : Paroxysmal nocturnal hemoglobinuria – only adults (18 years old or older)
Ravulizumab : Paroxysmal nocturnal haemoglobinuria – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Paroxysmal supraventricular tachycardia
Adenine Deoxy Nucleoside : Paroxysmal supraventricular tachycardias, Wolff-Parkinson-White Syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Adenine Deoxy Nucleoside : Paroxysmal supraventricular tachycardias, Wolff-Parkinson-White Syndrome – only adults (18 years old or older)
Antazoline : Paroxysmal arrhythmias of supraventricular origin – only adults (18 years old or older)
Neostigmine : Paroxysmal supraventricular tachycardia – only adults (18 - 65 years old)
Passing flatus
Magnesium hydroxide : Stomach discomfort, indigestion, hyperacidity, heartburn, flatulence – only children (1 year - 12 years old)
Magnesium hydroxide : Stomach discomfort, indigestion, hyperacidity, heartburn, flatulence – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pasteurella infection
Benzylpenicillin : Pasteurellosis – only newborns (0 - 40 days old)
Benzylpenicillin : Pasteurellosis – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Benzylpenicillin : Pasteurellosis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Patent ductus arteriosus
Alprostadil : Temporary maintenance of patency of the ductus arteriosus until corrective or palliative surgery – only newborns (0 - 40 days old)
Ibuprofen : Patent ductus arteriosus – only newborns (0 - 40 days old) , infants (40 days - 1 year old)
Pathological fracture
Zoledronic acid : Prevention of skeletal related events – only adults (18 years old or older)
Paucibacillary leprosy
Dapsone : Paucibacillary leprosy – only children (1 year - 12 years old)
Dapsone : Paucibacillary leprosy – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pemphigus vulgaris
Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylprednisolone : Pemphigus vulgaris – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Pemphigus vulgaris – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Peptic ulcer
Magaldrate : Ulcer of the upper digestive tract – only adults (18 years old or older)
Pantoprazole : Peptic ulcer – only adults (18 years old or older)
Percutaneous coronary intervention
Bivalirudin : Percutaneous coronary intervention – only adults (18 years old or older)
Percutaneous transluminal coronary angioplasty
Abciximab : Percutaneous coronary intervention – only adults (18 years old or older)
Isosorbide dinitrate : Percutaneous transluminal coronary angioplasty – only adults (18 years old or older)
Perennial allergic conjunctivitis
Azelastine : Non-seasonal (perennial) allergic conjunctivitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Cromoglicic acid : Seasonal and perennial allergic conjunctivitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Mizolastine : Seasonal allergic rhinoconjunctivitis (hay fever), perennial allergic rhinoconjunctivitis, urticaria – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Perennial allergic rhinitis with seasonal variation
Cetirizine : Seasonal and perennial allergic rhinitis, chronic idiopathic urticaria – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Perianal fistula due to Crohn's disease
Darvadstrocel : Complex perianal fistulas in nonactive/mildly active luminal Crohn’s disease – only adults (18 years old or older)
Periarthritis
Etofenamate : Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, folliculitis, periarthritis
Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Piroxicam : Osteoarthritis of superficial joints, acute musculoskeletal injuries, periarthritis, epicondylitis, tendinitis, tenosynovitis – only adults (18 years old or older)
Peribulbar infiltration of local anesthetic
Chloroprocaine : Peribulbar block – only adults (18 - 65 years old)
Levobupivacaine : Ophthalmic anaesthesia (peribulbar block) – only adults (18 years old or older)
Pericoronitis
Serrapeptase : Pericoronitis – only adults (18 years old or older)
Perineal wart
Imiquimod : External genital and perianal warts (condylomata acuminata) – only adults (18 years old or older)
Period pain
Dexketoprofen : Mild to moderate pain – only adults (18 years old or older)
Flurbiprofen : Dysmenorrhoea – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Ibuprofen : Dysmenorrhoea – women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Indometacin : Dysmenorrhea – women, only adults (18 - 65 years old)
Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older)
Naproxen : Dysmenorrhoea – women, only adults (18 years old or older)
Norethisterone : Dysfunctional uterine bleeding, polymenorrhoea, menorrhagia, dysmenorrhoea, metropathia haemorrhagia – women, only adults (18 - 65 years old)
Paracetamol : Dysmenorrhea – women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Periodic disease
Canacinumab : Familial Mediterranean fever (FMF) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Peripheral arterial occlusive disease
Clopidogrel : Peripheral arterial disease – only adults (18 years old or older)
Heparin : Acute peripheral arterial occlusion – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Heparin : Acute peripheral arterial occlusion – only adults (18 years old or older)
Peripheral block anesthesia
Bupivacaine : Major nerve block – only children (1 year - 12 years old)
Bupivacaine : Major nerve block – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Levobupivacaine : Peripheral nerve anaesthesia – only adults (18 years old or older)
Lidocaine : Peripheral block anesthesia – only adults (18 years old or older)
Peripheral blood stem cell graft
Lenograstim : Mobilisation of peripheral blood progenitor cells (PBPCs) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Peripheral circulatory disorder associated with type 2 diabetes mellitus
Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Peripheral edema
Furosemide : Oedema – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Furosemide : Oedema – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Peripheral gangrene
Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Peripheral neuropathic pain
Capsaicin : Peripheral neuropathic pain – only adults (18 years old or older)
Gabapentin : Peripheral neuropathic pain – only adults (18 years old or older)
Peripheral vascular disease
Pentoxifylline : Peripheral vascular disease, intermittent claudication, rest pain – only adults (18 years old or older)
Peripheral venous insufficiency
Diosmin : Venolymphatic insufficiency – only adults (18 years old or older)
Troxerutin : Oedema associated with chronic venous insufficiency – only adults (18 years old or older)
Persistent pulmonary hypertension of the newborn
Nitric oxide (NO) : Persistent pulmonary hypertension of the newborn (PPHN) – only newborns (0 - 40 days old)
Persistent trophoblastic disease
Etoposide : Gestational trophoblastic neoplasia – only adults (18 - 65 years old)
Ph positive ALL
Imatinib : Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Imatinib : Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) – only adults (18 years old or older)
Ponatinib : Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) – only adults (18 years old or older)
Pharyngeal candidiasis
Fluconazole : Oropharyngeal candidiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Miconazole : Candidosis of the oropharynx – only newborns (0 - 40 days old) , infants (40 days - 1 year old)
Miconazole : Candidosis of the oropharynx – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Posaconazole : Oropharyngeal candidiasis – only adults (18 years old or older)
Philadelphia chromosome positive chronic myelogenous leukaemia
Asciminib : Philadelphia chromosome-positive chronic myeloid leukaemia in chronic phase (Ph+ CML-CP) – only adults (18 years old or older)
Bosutinib : Philadelphia chromosome-positive chronic myelogenous leukaemia (Ph+ CML) – only adults (18 years old or older)
Dasatinib : Chronic myelogenous leukaemia (CML) Philadelphia chromosome positive (Ph+) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Dasatinib : Chronic myelogenous leukaemia (CML) Philadelphia chromosome positive (Ph+) – only adults (18 years old or older)
Imatinib : Chronic myeloid leukaemia (CML) Philadelphia chromosome (bcr-abl) positive (Ph+) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Imatinib : Chronic myeloid leukaemia (CML) Philadelphia chromosome (bcr-abl) positive (Ph+) – only adults (18 years old or older)
Nilotinib : Philadelphia chromosome positive chronic myelogenous leukaemia (CML) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Nilotinib : Philadelphia chromosome positive chronic myelogenous leukaemia (CML) – only adults (18 years old or older)
Photodermatitis
Clobetasone : Atopic dermatitis, irritant or allergic contact dermatitis, seborrhoeic dermatitis, nappy rash, photodermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Physical aggression
Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only elderly (65 years old or older)
Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only adults (18 - 65 years old)
Pituitary dependent hypercortisolism
Pasireotide : Cushing's disease – only adults (18 years old or older)
Pityriasis capitis
Ketoconazole : Dandruff – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pityriasis versicolor
Clotrimazole : Pityriasis versicolor
Econazole : Pityriasis versicolor – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Ketoconazole : Tinea versicolor – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Terbinafine : Pityriasis versicolor – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Plaque psoriasis
Adalimumab : Moderate to severe chronic plaque psoriasis – only adults (18 years old or older)
Adalimumab : Paediatric plaque psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Apremilast : Moderate to severe chronic plaque psoriasis – only adults (18 years old or older)
Apremilast : Moderate to severe paediatric plaque psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Bimekizumab : Moderate to severe plaque psoriasis – only adults (18 years old or older)
Brodalumab : Moderate to severe plaque psoriasis – only adults (18 years old or older)
Calcitriol : Plaque psoriasis – only adults (18 - 65 years old)
Certolizumab pegol : Plaque psoriasis – only adults (18 years old or older)
Deucravacitinib : Moderate to severe plaque psoriasis – only adults (18 years old or older)
Dimethyl fumarate : Moderate to severe plaque psoriasis – only adults (18 years old or older)
Efalizumab : Chronic plaque psoriasis – only adults (18 years old or older)
Etanercept : Plaque psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Guselkumab : Moderate to severe plaque psoriasis – only adults (18 years old or older)
Ixekizumab : Plaque psoriasis – only adults (18 years old or older)
Risankizumab : Moderate to severe plaque psoriasis – only adults (18 years old or older)
Secukinumab : Adult plaque psoriasis – only adults (18 years old or older)
Secukinumab : Paediatric plaque psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Tapinarof : Plaque psoriasis – only adults (18 years old or older)
Tazarotene : Mild to moderate plaque psoriasis – only adults (18 - 65 years old)
Tildrakizumab : Plaque psoriasis – only adults (18 years old or older)
Ustekinumab : Paediatric plaque psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Ustekinumab : Plaque psoriasis – only adults (18 years old or older)
Pleural effusion due to malignant neoplastic disease
Bleomycin : Malignant pleural effusion – only adults (18 years old or older)
Pneumocystosis pneumonia
Atovaquone : Mild to moderate pneumocystis pneumonia caused by Pneumocystis jiroveci – only adults (18 - 65 years old)
Pneumonia caused by respiratory syncytial virus
Nirsevimab : Respiratory Syncytial Virus (RSV) lower respiratory tract disease – only newborns (0 - 40 days old) , infants (40 days - 1 year old)
RSV glycoprotein F antigen : Lower respiratory tract disease (LRTD) caused by respiratory syncytial virus – only adults (18 years old or older)
Poisoning by drug AND/OR medicinal substance
Mannitol : Elimination of renally excreted toxic substances in poisoning – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Poisoning by iron
Deferoxamine : Acute iron poisoning – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Poisoning by paracetamol
Acetylcysteine : Treatment of paracetamol overdose
Poisoning by pyrimethamine
Calcium folinate : Antidote for pyrimethamine toxicity – only adults (18 years old or older)
Poisoning due to chemical substance
Charcoal activated : Acute oral poisoning, drug overdose – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Charcoal activated : Acute oral poisoning, drug overdose – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Pollinosis
Chlorphenamine : Hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy – only children (1 year - 12 years old) , elderly (65 years old or older)
Chlorphenamine : Hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Mequitazine : Hay fever, perennial rhinitis, urticaria, allergic pruritis, insect bites, stings – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Polyarteritis nodosa
Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Dexamethasone : Polyarteritis nodosa – only adults (18 years old or older)
Prednisolone : Polyarteritis nodosa – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Polycystic ovary syndrome
Bromocriptine : Polycystic ovary syndrome – women, only adults (18 - 65 years old)
Polygenic hypercholesterolaemia
Alirocumab : Primary heterozygous familial hypercholesterolaemia, primary non-familial hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older)
Evolocumab : Primary hypercholesterolaemia (heterozygous familial and non-familial), mixed dyslipidaemia – only adults (18 years old or older)
Polymenorrhea
Norethisterone : Dysfunctional uterine bleeding, polymenorrhoea, menorrhagia, dysmenorrhoea, metropathia haemorrhagia – women, only adults (18 - 65 years old)
Polymyalgia rheumatica
Dexamethasone : Polymyalgia rheumatica – only adults (18 years old or older)
Methylprednisolone : Polymyalgia rheumatica – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Polymyalgia rheumatica – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Polymyositis
Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylprednisolone : Polymyositis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Polymyositis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Polyp of nasal cavity
Mometasone : Nasal polyposis – only adults (18 years old or older)
Polyp of nasal cavity and/or nasal sinus
Budesonide : Nasal polyps – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Polyuria
Desmopressin : Nocturia – only adults (18 - 65 years old)
Porphobilinogen synthase deficiency
Givosiran : Acute hepatic porphyria (AHP) – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Portal hypertension
Propranolol : Portal hypertension – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Post-essential thrombocythaemia myelofibrosis
Fedratinib : Primary myelofibrosis, post polycythaemia vera myelofibrosis, post essential thrombocythaemia myelofibrosis – only adults (18 years old or older)
Post-polycythaemia vera myelofibrosis
Fedratinib : Primary myelofibrosis, post polycythaemia vera myelofibrosis, post essential thrombocythaemia myelofibrosis – only adults (18 years old or older)
Post-transplant lymphoproliferative disorder
Tabelecleucel : Epstein-Barr virus positive post-transplant lymphoproliferative disease (EBV+ PTLD) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Posterior uveitis
Methylprednisolone : Posterior uveitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Posterior uveitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Postherpetic neuralgia
Attenuated varicella-zoster virus : Herpes zoster, post-herpetic neuralgia (PHN) – only adults (18 years old or older)
Postmenopausal hormone replacement therapy
Progesterone : Hormone replacement therapy (HRT) – women, only adults (18 - 65 years old)
Postmenopausal osteoporosis
Abaloparatide : Osteoporosis – women, only adults (18 years old or older)
Bazedoxifene : Postmenopausal osteoporosis – women, only adults (18 years old or older)
Calcitonin : Established postmenopausal osteoporosis – women, only adults (18 years old or older)
Calcitonin : Established postmenopausal osteoporosis – women, only adults (18 years old or older)
Calcitriol : Post-menopausal osteoporosis – only adults (18 years old or older)
Raloxifene : Post-menopausal osteoporosis – women, only adults (18 years old or older)
Raloxifene : Post-menopausal osteoporosis – women, only adults (18 years old or older)
Risedronic acid : Postmenopausal osteoporosis – women, only adults (18 years old or older)
Postmyocardial infarction syndrome
Prednisolone : Postmyocardial infarction syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Postoperative intestinal obstruction
Trimebutine : Postoperative paralytic ileus – only adults (18 years old or older)
Postoperative nausea
Granisetron : Post-operative nausea and vomiting (PONV) – only adults (18 years old or older)
Postoperative nausea and vomiting
Granisetron : Post-operative nausea and vomiting (PONV) – only adults (18 years old or older)
Haloperidol : Postoperative nausea and vomiting – only adults (18 years old or older)
Ondansetron : Post operative nausea and vomiting (PONV) – only minors (0 - 18 years old)
Ondansetron : Post operative nausea and vomiting (PONV) – only adults (18 years old or older)
Tropisetron : Post-operative nausea and vomiting – only adults (18 - 65 years old)
Postoperative pain
Acemetacin : Osteoarthritis, rheumatoid arthritis, pain, inflammation – only adults (18 - 65 years old)
Dihydrocodeine : Post-operative pain – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Levobupivacaine : Postoperative pain – only adults (18 years old or older)
Nalbuphine : Moderate to severe pain, postoperative pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Nalbuphine : Moderate to severe pain, postoperative pain – only adults (18 years old or older)
Parecoxib : Postoperative pain – only adults (18 years old or older)
Sufentanil : Postoperative pain – only adults (18 years old or older)
Postoperative retention of urine
Neostigmine : Post-operative urinary retention – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pyridostigmine : Paralytic ileus, post-operative urinary retention – only adults (18 years old or older)
Postoperative uveitis
Loteprednol : Post-operative inflammation following ocular surgery – only adults (18 years old or older)
Rimexolone : Postoperative inflammation following ocular surgery – only adults (18 years old or older)
Postoperative vomiting
Granisetron : Post-operative nausea and vomiting (PONV) – only adults (18 years old or older)
Postpartum depression
Zuranolone : Postpartum depression – women, only adults (18 - 65 years old)
Postpartum hemorrhage
Carboprost : Post-partum haemorrhage – women, only adults (18 - 65 years old)
Ergometrine : Post-partum haemorrhage – women, only adults (18 - 65 years old)
Postpartum hemorrhage co-occurrent and due to uterine rupture following obstructed labor
Oxytocin : Postpartum uterine haemorrhage – women, only adults (18 - 65 years old)
Oxytocin : Postpartum uterine haemorrhage – women, only adults (18 - 65 years old)
Posttransplant hyperlipidemia
Pravastatin : Post transplantation hyperlipidaemia – only adults (18 years old or older)
Posttraumatic stress disorder
Paroxetine : Posttraumatic stress disorder – only adults (18 years old or older)
Sertraline : Post traumatic stress disorder (PTSD) – only adults (18 years old or older)
Prader-Willi syndrome
Somatropin : Prader-Willi syndrome (PWS) – only minors (0 - 18 years old)
Precursor T-cell lymphoblastic lymphoma
Nelarabine : T-cell lymphoblastic lymphoma (T-LBL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Nelarabine : T-cell lymphoblastic lymphoma (T-LBL) – only adults (18 years old or older)
Preinfarction syndrome
Abciximab : Unstable angina – only adults (18 years old or older)
Acetylsalicylic acid : Stable and unstable angina pectoris – only adults (18 years old or older)
Bivalirudin : Treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction – only adults (18 years old or older)
Dalteparin : Unstable angina, non-Q wave myocardial infarction – only adults (18 years old or older)
Eptifibatide : Unstable angina, non-Q-wave myocardial infarction – only adults (18 years old or older)
Heparin : Unstable angina pectoris – only adults (18 years old or older)
Nadroparin : Unstable angina, non-Q wave myocardial infarction – only adults (18 years old or older)
Tirofiban : Acute coronary syndromes without ST elevation (NSTE-ACS) – only adults (18 years old or older)
Premature ejaculation
Dapoxetine : Premature ejaculation (PE) – men, only adults (18 - 65 years old)
Premature labor
Atosiban : Pre-term birth – women, only adults (18 - 65 years old)
Premedication for anesthetic procedure
Diazepam : Premedication before surgery or dental procedures – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Diazepam : Premedication before surgery or dental procedures – only elderly (65 years old or older)
Diazepam : Premedication before surgery or dental procedures – only adults (18 - 65 years old)
Lorazepam : Premedication – only elderly (65 years old or older)
Lorazepam : Premedication – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Lorazepam : Premedication – only adults (18 - 65 years old)
Midazolam : Premedication – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Midazolam : Premedication – only adults (18 - 65 years old)
Premenstrual tension syndrome
Norethisterone : Pre-menstrual syndrome – women, only adults (18 - 65 years old)
Preoperative disinfection of skin
Hydrogen peroxide : Disinfection – only adults (18 years old or older)
Povidone iodine : Antisepsis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Preparation of bowel for surgery
Neomycin : Pre-operative sterilisation of the bowel – only children (1 year - 12 years old)
Neomycin : Pre-operative sterilisation of the bowel – only adolescents (12 years - 18 years old)
Neomycin : Pre-operative sterilisation of the bowel – only adults (18 years old or older)
Prevention of deep vein thrombosis
Dalteparin : Prophylaxis of venous thromboembolism in medical patients – only adults (18 years old or older)
Prevention of dental caries
Sodium fluoride : Prevention of dental caries – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Primary adenocarcinoma of esophagogastric junction
Docetaxel : Gastric adenocarcinoma, adenocarcinoma of the gastroesophageal junction – only adults (18 years old or older)
Ramucirumab : Advanced gastric cancer, gastro-oesophageal junction adenocarcinoma – only adults (18 years old or older)
Primary adrenocortical insufficiency
Dexamethasone : Primary adrenocortical insufficiency – only adults (18 years old or older)
Fludrocortisone : Primary adrenocortical insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylprednisolone : Primary adrenocortical insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary biliary cirrhosis
Elafibranor : Primary biliary cholangitis – only adults (18 years old or older)
Obeticholic acid : Primary biliary cholangitis – only adults (18 years old or older)
Ursodeoxycholic acid : Primary biliary cholangitis – only adults (18 years old or older)
Primary cutaneous diffuse large cell B-cell lymphoma
Tisagenlecleucel : Relapsed or refractory diffuse large B-cell lymphoma (DLBCL) – only adults (18 - 65 years old)
Primary cutaneous T-cell lymphoma
Bexarotene : Cutaneous T-cell lymphoma (CTCL) – only adults (18 years old or older)
Primary differentiated carcinoma of thyroid gland
Lenvatinib : Differentiated thyroid carcinoma – only adults (18 years old or older)
Sorafenib : Differentiated thyroid carcinoma – only adults (18 years old or older)
Primary dysmenorrhea
Dexibuprofen : Primary dysmenorrhoea – women, only adults (18 years old or older)
Mefenamic acid : Primary dysmenorrhoea – women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Nimesulide : Primary dysmenorrhea – women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Primary gout
Allopurinol : Gouty arthritis, skin tophi, nephrolithiasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Allopurinol : Gouty arthritis, skin tophi, nephrolithiasis – only adults (18 years old or older)
Colchicine : Acute gout – only adults (18 years old or older)
Lesinurad : Hyperuricaemia in gout – only adults (18 years old or older)
Naproxen : Acute gout – only adults (18 years old or older)
Primary hyperaldosteronism
Spironolactone : Primary aldosteronism – only adults (18 years old or older)
Primary hypercholesterolemia
Atorvastatin : Primary hypercholesterolaemia, combined hyperlipidaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Bempedoic acid : Primary hypercholesterolaemia – only adults (18 years old or older)
Colesevelam : Primary hypercholesterolaemia – only adults (18 years old or older)
Ezetimibe : Primary hypercholesterolaemia – only adults (18 years old or older)
Fluvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older)
Gemfibrozil : Severe hypertriglyceridaemia, mixed hyperlipidaemia, primary hypercholesterolaemia – only adults (18 years old or older)
Inclisiran : Primary hypercholesterolaemia – only adults (18 years old or older)
Pitavastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older)
Pravastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 years old or older)
Rosuvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only elderly (65 years old or older)
Rosuvastatin : Primary hypercholesterolaemia, mixed dyslipidaemia – only adults (18 - 65 years old)
Simvastatin : Primary hypercholesterolemia, mixed dyslipidaemia – only adults (18 years old or older)
Primary hyperoxaluria, type I
Lumasiran : Primary hyperoxaluria type 1 (PH1) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Nedosiran : Primary hyperoxaluria type 1 – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary IgA nephropathy
Sparsentan : Primary immunoglobulin A nephropathy with a urine protein excretion ≥1.0 g/day – only adults (18 years old or older)
Primary immune deficiency disorder
Human normal immunoglobulin G : Primary immunodeficiency syndromes with impaired antibody production, secondary immunodeficiencies (SID) – only minors (0 - 18 years old) , adults (18 - 65 years old)
Immunoglobulins, normal human, IV : Primary immunodeficiency syndromes (PID) with impaired antibody production – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary insomnia
Melatonin : Primary insomnia – only adults (18 years old or older)
Primary irritant dermatitis
Alclometasone : Eczema, primary irritant and allergic dermatitis – only adults (18 years old or older)
Betamethasone : Irritant contact dermatitis, allergic contact dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Clobetasone : Atopic dermatitis, irritant or allergic contact dermatitis, seborrhoeic dermatitis, nappy rash, photodermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary malignant neoplasm of adrenal cortex
Mitotane : Adrenal cortical carcinoma (ACC) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Mitotane : Adrenal cortical carcinoma (ACC) – only adults (18 years old or older)
Primary malignant neoplasm of endometrium
Dostarlimab : Endometrial cancer – only adults (18 years old or older)
Dostarlimab : Endometrial cancer – only adults (18 years old or older)
Primary malignant neoplasm of rectum
Bevacizumab : Metastatic carcinoma of the colon or rectum – only adults (18 years old or older)
Primary malignant neoplasm of testis
Bleomycin : Testicular carcinoma (seminoma and non-seminoma) – men, only adults (18 years old or older)
Primary malignant neoplasm of the peritoneum
Rucaparib : Epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer – only adults (18 years old or older)
Primary malignant neoplasm of urethra
Vinflunine : Transitional cell carcinoma of the urothelial tract – only elderly (65 years old or older)
Vinflunine : Transitional cell carcinoma of the urothelial tract – only adults (18 - 65 years old)
Primary nocturnal enuresis
Desmopressin : Primary nocturnal enuresis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Primary open angle glaucoma
Acetazolamide : Chronic simple glaucoma (open angle) – only adults (18 years old or older)
Apraclonidine : Chronic glaucoma – only adults (18 years old or older)
Betaxolol : Ocular hypertension, chronic open angle glaucoma – only adults (18 years old or older)
Bimatoprost : Chronic open-angle glaucoma, ocular hypertension – only adults (18 years old or older)
Carteolol : Ocular hypertension, chronic open angle glaucoma, secondary glaucomas – only adults (18 years old or older)
Levobunolol : Chronic open-angle glaucoma, ocular hypertension – only adults (18 years old or older)
Pilocarpine : Chronic simple glaucoma – only adults (18 years old or older)
Timolol : Elevated intra-ocular pressure, chronic open-angle glaucoma – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Primary prevention of cardiovascular disease
Pravastatin : Primary prevention of cardiovascular disease – only adults (18 years old or older)
Rosuvastatin : Primary prevention of cardiovascular disease – only adults (18 - 65 years old)
Primary syphilis
Doxycycline : Primary and secondary syphilis – only adults (18 years old or older)
Primary transitional cell carcinoma of overlapping lesion of urinary organ
Pembrolizumab : Locally advanced or metastatic urothelial carcinoma with PD-L1 with CPS ≥10 – only adults (18 years old or older)
Prinzmetal angina
Amlodipine : Chronic stable angina pectoris, vasospastic angina – only adults (18 years old or older)
Proctitis
Fluocortolone : hemorrhoids, non-infectious proctitis, anal eczema – only adults (18 years old or older)
Proctoscopy
Lidocaine : Bronchoscopy, gastroscopy, colonoscopy, rectoscopy – only adults (18 years old or older)
Productive cough
Guaifenesin : Productive cough – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Progressive intrahepatic cholestasis
Odevixibat : Progressive familial intrahepatic cholestasis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Progressive myositis ossificans
Palovarotene : Fibrodysplasia ossificans progressiva – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Progressive relapsing multiple sclerosis
Methylprednisolone : Acute exacerbations of multiple sclerosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Methylprednisolone : Acute exacerbations of multiple sclerosis – only adults (18 years old or older)
Ublituximab : Relapsing forms of multiple sclerosis – only adults (18 years old or older)
Prolactinoma
Bromocriptine : Prolactinoma – only adults (18 years old or older)
Bromocriptine : Prolactinoma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Proliferative diabetic retinopathy
Ranibizumab : Proliferative diabetic retinopathy (PDR) – only adults (18 years old or older)
Prostate-specific antigen monitoring
Flotufolastat ¹⁸F : Detection of prostate-specific membrane antigen positive lesions in patients with prostate cancer – men, only adults (18 years old or older)
Piflufolastat ¹⁸F : Detection of prostate-specific membrane antigen positive lesions in patients with prostate cancer – men, only adults (18 years old or older)
Prurigo
Fluocinonide : Prurigo – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prurigo nodularis
Betamethasone : Prurigo nodularis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Clobetasone : Otitis externa, prurigo nodularis, insect bite reactions – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Hydrocortisone : Prurigo nodularis, neurodermatoses, otitis externa, intertrigo, napkin rash – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pruritus ani
Cinchocaine : Hemorrhoids, anal fissure, pruritus ani – only adults (18 years old or older)
Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Pruritus of vulva
Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Pseudocroup
Budesonide : Pseudocroup (laryngitis subglottica) – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Psoriasis
Alefacept : Psoriasis – only adults (18 years old or older)
Ciclosporin : Psoriasis – only adults (18 years old or older)
Coal tar : Psoriasis of the skin and scalp – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Infliximab : Psoriasis – only adults (18 years old or older)
Methotrexate : Psoriasis – only adults (18 years old or older)
Psoriatic arthritis
Abatacept : Psoriatic Arthritis – only adults (18 years old or older)
Adalimumab : Ankylosing spondylitis, axial spondyloarthritis, psoriatic arthritis – only adults (18 years old or older)
Apremilast : Psoriatic arthritis – only adults (18 years old or older)
Bimekizumab : Psoriatic arthritis – only adults (18 years old or older)
Certolizumab pegol : Psoriatic arthritis – only adults (18 years old or older)
Etanercept : Psoriatic arthritis – only adults (18 years old or older)
Golimumab : Psoriatic arthritis – only adults (18 years old or older)
Guselkumab : Psoriatic arthritis – only adults (18 years old or older)
Infliximab : Psoriatic arthritis – only adults (18 years old or older)
Ixekizumab : Psoriatic arthritis – only adults (18 years old or older)
Leflunomide : Psoriatic arthritis – only adults (18 years old or older)
Secukinumab : Psoriatic arthritis – only adults (18 years old or older)
Tofacitinib : Psoriatic arthritis
Upadacitinib : Psoriatic arthritis – only adults (18 years old or older)
Ustekinumab : Psoriatic arthritis – only adults (18 years old or older)
Psychomotor agitation
Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only elderly (65 years old or older)
Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only adults (18 - 65 years old)
Trifluoperazine : Psychoses, mental subnormality, nausea and vomiting – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Psychomotor epilepsy
Primidone : Grand mal and psychomotor (temporal lobe) epilepsy, focal or Jacksonian seizures, myoclonic jerks, akinetic attacks – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Psychosis co-occurrent and due to Parkinson's disease
Clozapine : Psychosis during the course of Parkinson's disease – only adults (18 years old or older)
Psychotic disorder
Pimozide : Psychotic disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Sulpiride : Schizophrenia – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Zuclopenthixol : Schizophrenia, psychoses – only adults (18 years old or older)
Pulmonary arterial hypertension associated with connective tissue disease
Riociguat : Pulmonary arterial hypertension (PAH) – only adults (18 years old or older)
Pulmonary aspergillosis
Prednisolone : Pulmonary aspergillosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pulmonary edema
Aminophylline : Pulmonary oedema, paroxysmal nocturnal dyspnoea, status asthmaticus, acute bronchospasm – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Furosemide : Pulmonary oedema – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Furosemide : Pulmonary oedema – only adults (18 years old or older)
Pulmonary embolism
Dabigatran : Deep vein thrombosis and pulmonary embolism – only adults (18 years old or older)
Dabigatran : Recurrent deep vein thrombosis and pulmonary embolism – only adults (18 years old or older)
Dalteparin : Venous thromboembolism (VTE), deep vein thrombosis (DVT), pulmonary embolism (PE) – only adults (18 years old or older)
Enoxaparin : Deep vein thrombosis (DVT), pulmonary embolism (PE) – only adults (18 years old or older)
Heparin : Pulmonary embolism – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Heparin : Pulmonary embolism – only adults (18 years old or older)
Nadroparin : Deep venous thrombosis, pulmonary embolism – only adults (18 years old or older)
Rivaroxaban : Deep vein thrombosis (DVT), pulmonary embolism (PE) – only adults (18 years old or older)
Pulmonary emphysema
Metaproterenol : Pulmonary emphysema – only adults (18 - 65 years old)
Salbutamol : Pulmonary emphysema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Salbutamol : Pulmonary emphysema – only adults (18 years old or older)
Pulmonary hypertensive arterial disease
Ambrisentan : Pulmonary arterial hypertension (PAH) classified as WHO functional class II and III – only adults (18 years old or older)
Bosentan : Pulmonary arterial hypertension (PAH) – only adults (18 years old or older)
Macitentan : Pulmonary arterial hypertension functional class (FC) II to III – only adults (18 years old or older)
Selexipag : Pulmonary arterial hypertension (PAH) – only adults (18 years old or older)
Sildenafil : Pulmonary arterial hypertension – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Sildenafil : Pulmonary arterial hypertension classified as WHO functional class II and III – only adults (18 years old or older)
Sitaxentan : Pulmonary arterial hypertension (PAH) classified as WHO functional class III – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Sotatercept : Pulmonary arterial hypertension – only adults (18 years old or older)
Pulmonary hypertensive venous disease
Nitric oxide (NO) : Pulmonary hypertension associated with heart surgery – only adults (18 - 65 years old)
Nitric oxide (NO) : Pulmonary hypertension associated with heart surgery – only newborns (0 - 40 days old)
Pulmonary lymphangioleiomyomatosis
Sirolimus : Sporadic lymphangioleiomyomatosis – only adults (18 years old or older)
Pulmonary sarcoidosis
Methylprednisolone : Pulmonary sarcoidosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Pulmonary tuberculosis
Pretomanid : Pulmonary tuberculosis due to Mycobacterium tuberculosis – only adults (18 years old or older)
Rifabutin : Pulmonary tuberculosis – only adults (18 years old or older)

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